The Preventive Effect of Biochanin A on Bone Loss in Ovariectomized Rats: Involvement in Regulation of Growth and Activity of Osteoblasts and Osteoclasts

Table 2

Effect of treatments on femoral bone mineral density (BMD), bone mineral content (BMC), and BV/TV of the left femur.

Treatment group; (𝑛=10)	Bone mineral density; (BMD) (mg/cm^2)	Bone mineral content; (BMC) (g)	Bone volume; (BV/TV) (%)
Sham	192.0±8.0^b	0.48±0.4^b	35.5±5.4^b
OVX	164.0±6.7^a	0.37±0.3^a	12.6±3.3^a
OVX + E2	185.0±5.0^b	0.44±0.5^b	28.7±4.3^b
OVX + BCA	188.0±8.6^b	0.48±0.6^b	31.8±4.5^b

BMD (mg/cm²) and BMC (g) were measured by Dual Energy X-Ray Absorptiometry. Values are expressed as means ± SD. Means within a column with different superscript letters are significantly different (𝑃<0.05, ANOVA and the Fisher test). ^a𝑃<0.05, when compared with the sham groups; ^b𝑃<0.05, when compared with the OVX group.