Validation of the Antidiabetic and Hypolipidemic Effects of Hawthorn by Assessment of Gluconeogenesis and Lipogenesis Related Genes and AMP-Activated Protein Kinase Phosphorylation

Figure 3

Semiquantitive RT-PCR analysis on (a) PEPCK, (b) SREBP1c, (c) FAS, (d) apo C-III, (e) apoA-I, and (f) SREBP2 mRNA expression in liver tissue of the mice by oral gavage extracts of hawthorn for 4 weeks. All values are means ± S.E. (𝑛=9). ^##𝑃<0.01, ^###𝑃<0.001 compared with the control (CON) group; ^∗𝑃<0.05, ^∗∗𝑃<0.01, ^∗∗∗𝑃<0.001 compared with the high-fat + vehicle (distilled water) (HF) group. K1, K2, K3, extracts of hawthorn.