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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 602672, 8 pages
Research Article

Research on Zheng Classification Fusing Pulse Parameters in Coronary Heart Disease

1Laboratory of Information Access and Synthesis of TCM Four Diagnostic, Center for TCM Information Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
2Center for Mechatronics Engineering, East China University of Science and Technology, Shanghai 200237, China

Received 11 January 2013; Revised 28 March 2013; Accepted 6 April 2013

Academic Editor: Aiping Lu

Copyright © 2013 Rui Guo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This study was conducted to illustrate that nonlinear dynamic variables of Traditional Chinese Medicine (TCM) pulse can improve the performances of TCM Zheng classification models. Pulse recordings of 334 coronary heart disease (CHD) patients and 117 normal subjects were collected in this study. Recurrence quantification analysis (RQA) was employed to acquire nonlinear dynamic variables of pulse. TCM Zheng models in CHD were constructed, and predictions using a novel multilabel learning algorithm based on different datasets were carried out. Datasets were designed as follows: dataset1, TCM inquiry information including inspection information; dataset2, time-domain variables of pulse and dataset1; dataset3, RQA variables of pulse and dataset1; and dataset4, major principal components of RQA variables and dataset1. The performances of the different models for Zheng differentiation were compared. The model for Zheng differentiation based on RQA variables integrated with inquiry information had the best performance, whereas that based only on inquiry had the worst performance. Meanwhile, the model based on time-domain variables of pulse integrated with inquiry fell between the above two. This result showed that RQA variables of pulse can be used to construct models of TCM Zheng and improve the performance of Zheng differentiation models.