<i  >Phyllanthus</i> Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NF<svg     style="vertical-align:-0.0pt;width:12.675px;" id="M1" height="10.475" version="1.1" viewBox="0 0 12.675 10.475" width="12.675"  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg">
	
		
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</svg>B, and Hypoxia)

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td align="left" rowspan="2"><i>Phyllanthus  </i>
										 species </td><td align="center" rowspan="2">Extracts </td><td align="center"><svg height="15.65" id="M8" style="vertical-align:-3.39066pt" version="1.1" viewbox="0 0 79.462502 15.65" width="79.462502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.362)"><path d="M303 0h-265v28q62 5 76 19.5t14 77.5v400q0 63 -14 77.5t-76 19.5v28h265v-28q-62 -5 -76 -19.5t-14 -77.5v-400q0 -64 14 -78t76 -19v-28z" id="x49"></path></g><g transform="matrix(.017,-0,0,-.017,5.859,11.362)"><path d="M614 175l29 -10q-33 -109 -57 -154q-121 -26 -184 -26q-90 0 -160.5 29t-112.5 77t-63.5 105.5t-21.5 119.5q0 157 108 253t277 96q36 0 71.5 -5t69 -13.5t36.5 -8.5q15 -102 20 -150l-29 -8q-20 79 -66.5 114t-128.5 35q-119 0 -187.5 -86t-68.5 -207
q0 -140 73.5 -227.5t188.5 -87.5q73 0 119.5 37.5t86.5 116.5z" id="x43"></path></g>
<g transform="matrix(.012,-0,0,-.012,17.162,15.45)"><path d="M153 550l-26 -186q79 31 111 31q90 0 141.5 -51t51.5 -119q0 -93 -89 -166q-85 -69 -173 -71q-32 0 -61.5 11.5t-41.5 23.5q-18 17 -17 34q2 16 22 33q14 9 26 -1q61 -50 124 -50q60 0 93 43.5t33 104.5q0 69 -41.5 110t-121.5 41q-53 0 -102 -20l38 305h286l6 -8
l-26 -65h-233z" id="x35"></path></g><g transform="matrix(.012,-0,0,-.012,22.874,15.45)"><path d="M241 635q53 0 94 -28.5t63.5 -76t33.5 -102.5t11 -116q0 -58 -11 -112.5t-34 -103.5t-63.5 -78.5t-94.5 -29.5t-95 28t-64.5 75t-34.5 102.5t-11 118.5q0 58 11.5 112.5t34.5 103t64.5 78t95.5 29.5zM238 602q-32 0 -55.5 -25t-35.5 -68t-17.5 -91t-5.5 -105
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<g transform="matrix(.017,-0,0,-.017,32.988,11.362)"><path d="M535 290h-212v-206h-58v206h-213v50h213v193h58v-193h212v-50zM535 -22h-483v50h483v-50z" id="xB1"></path></g>
<g transform="matrix(.017,-0,0,-.017,46.738,11.362)"><path d="M409 504l-29 -5q-16 60 -44.5 96t-86.5 36q-54 0 -82.5 -32t-28.5 -77q0 -51 30.5 -82.5t96.5 -65.5l35.5 -18t33 -19.5t33.5 -23.5l27 -25.5t24.5 -32t13.5 -36.5t6 -45q0 -80 -62 -134.5t-160 -54.5q-47 0 -98 15q-22 7 -50 21q-8 23 -27 155l30 7q7 -27 18 -52
t30 -51.5t49 -42.5t67 -16q56 0 88 32.5t32 87.5q0 51 -31.5 82t-98.5 67q-80 44 -110 73q-55 53 -55 124q0 75 56 126.5t150 51.5q53 0 126 -23z" id="x53"></path></g><g transform="matrix(.017,-0,0,-.017,54.608,11.362)"><path d="M517 162l29 -4q-18 -100 -35 -158h-482v28q68 5 83.5 20t15.5 77v398q0 66 -13 80t-73 19v28h446q0 -8 8 -144l-29 -4q-11 51 -32 85q-11 17 -35 23t-78 6h-76q-23 0 -28 -5t-5 -27v-228h94q67 0 83 12t25 63h29v-191h-29q-10 54 -26 65.5t-81 11.5h-95v-189
q0 -65 24 -81q19 -13 104 -13q57 0 83 7t43 27q28 33 50 94z" id="x45"></path></g><g transform="matrix(.017,-0,0,-.017,64.263,11.362)"><path d="M861 0h-263v28q61 5 73 22t12 97l-4 408h-4l-244 -548h-20l-224 534h-2l-15 -285q-5 -98 -3 -166q1 -34 19.5 -45t72.5 -17v-28h-233v28q45 5 62.5 17t22.5 43q11 65 19 183l14 208q3 36 3.5 55t-2.5 37.5t-6.5 25t-16.5 13t-25.5 8t-39.5 4.5v28h164l228 -501l232 501
h170v-28q-68 -6 -81 -21.5t-11 -91.5l9 -362q2 -80 15 -97t78 -22v-28z" id="x4D"></path></g>
</svg> (<i>μ</i>g/mL)</td></tr><tr class="thead"><td align="center">PC-3</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td align="left" rowspan="2"><i>P.  </i>
										 <i>amarus (PA)  </i></td><td align="center">Aqueous (H<sub>2</sub>O)</td><td align="center">178.3 ± 2.8</td></tr><tr><td align="center">Methanolic (MeOH)</td><td align="center">84.3 ± 1.1</td></tr><tr><td align="left" rowspan="2"><i>P.  </i>
										 <i>niruri (PN)  </i></td><td align="center">Aqueous (H<sub>2</sub>0)</td><td align="center">155.0 ± 1.2</td></tr><tr><td align="center">Methanolic (MeOH)</td><td align="center">117.7 ± 2.1</td></tr><tr><td align="left" rowspan="2"><i>P.  </i>
										 <i>urinaria (PU)  </i></td><td align="center">Aqueous (H<sub>2</sub>O)</td><td align="center">155.7 ± 2.1</td></tr><tr><td align="center">Methanolic (MeOH)</td><td align="center">54.2 ± 2.1</td></tr><tr><td align="left" rowspan="2"><i>P.  </i>
										 <i>watsonii (PW)  </i></td><td align="center">Aqueous (H<sub>2</sub>O)</td><td align="center">156.7 ± 2.4</td></tr><tr><td align="center">Methanolic (MeOH)</td><td align="center">100.5 ± 1.2</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Treatment of PC-3 cells at different IC<sub>50</sub> values of <i>Phyllanthus</i> extracts [<a href="/journals/ecam/2013/609581/#B21">8</a>].

Evidence-Based Complementary and Alternative Medicine

tab1

Table 1

Table 1: <i  >Phyllanthus</i> Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NF<svg     style="vertical-align:-0.0pt;width:12.675px;" id="M1" height="10.475" version="1.1" viewBox="0 0 12.675 10.475" width="12.675"  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg">
	
		
			<g transform="matrix(.022,-0,0,-.022,.062,10.412)"><path id="x1D73F" d="M276 462l-36 -168l129 101q83 67 140 67q68 0 68 -50q0 -62 -59 -62q-18 0 -28.5 7t-13.5 16t-10.5 16t-19.5 7q-14 0 -49 -29l-114 -93l112 -199q18 -31 39 -41.5t64 -10.5l-5 -23h-269l5 23h29q28 0 28 15q0 14 -13 36l-60 107l-42 -181h-116l82 363q4 15 4 28
q0 17 -26 17q-15 0 -32 -3l-3 23z" /></g>

		
	
</svg>B, and Hypoxia) 

Table 1 | Phyllanthus Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NF
	
		
			

		
	
B, and Hypoxia) 

Evidence-Based Complementary and Alternative Medicine

Phyllanthus Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NF B, and Hypoxia)

Table 1

Phyllanthus Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NFB, and Hypoxia)