Tanshinone IIA and Cryptotanshinone Prevent Mitochondrial Dysfunction in Hypoxia-Induced H9c2 Cells: Association to Mitochondrial ROS, Intracellular Nitric Oxide, and Calcium Levels

Figure 2

Effects of TIIA and CT on hypoxia-induced decrease in intracellular superoxide level and NADPH oxidase activity. (a) Images of cells labelled with DHE in normoxia and hypoxia groups. (b) The quantified value of DHE fluorescence intensity. Represented data are mean value of 500 each cells with 4 independent experiments. (c) Quantitative value of NADPH oxidase activity. Data shown are representative of 4 independent experiments.  **𝑃<0.01  versus normoxia,  ***𝑃<0.001versus normoxia.

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