Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Fig 2

Research Article

Interaction of Natural Dietary and Herbal Anionic Compounds and Flavonoids with Human Organic Anion Transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11)

Figure 2

Inhibitory effects of the nine test compounds on hOAT1-mediated PAH uptake. Ten-minute uptake of [3H]PAH (1 μM) was measured in CHO-hOAT1 cells in the absence and presence of test compounds (50 μM) or probenecid (1000 μM). Data represent hOAT1-mediated transport specifically, that is, data have been corrected for background PAH accumulation measured in empty vector transfected cells. Values are . of triplicate values from a representative experiment. , and as determined by one-way ANOVA followed by Dunnett’s t-test.

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