The Antiobesity Effect of Polygonum aviculare L. Ethanol Extract in High-Fat Diet-Induced Obese Mice

Table 2

The effects of PAE on body weight, food intake, and adipose tissue weight in HFD-fed obese mice.

	ND	HFD	HFD + PAE	HFD + Orlistat	HFD + BPT
Initial body weight, g	19.54±0.21	19.64±0.19	19.64±0.21	19.64±0.20	19.64±0.20
Final body weight, g	24.18±0.26	29.17±0.48^###	26.94±0.30 **	28.07±0.17	28.11±0.98
Body weight gain, g/day	4.54±0.16	9.63±0.32^###	7.31±0.47 *	8.37±0.25 *	8.49±0.81
Food intake, g/day	4.23±0.13	2.33±0.02^###	2.30±0.05	2.35±0.03	2.29±0.10
White adipose tissue weight
Subcutaneous, g/100 g body weight	0.94±0.04	2.85±0.54^##	2.29±0.36	2.43±0.15	2.92±0.42
Epididymal, g/100 g body weight	1.13±0.14	5.29±0.58^###	3.73±0.35 *	4.19±0.15	4.78±0.81
Retroperitoneal, g/100 g body weight	0.36±0.11	2.22±0.39^##	1.28±0.13 *	1.56±0.13	1.68±0.30

Values are expressed as means ± SEM (n = 5–7).
^##𝑃<0.01 and ^###𝑃<0.001 compared with the ND group; *𝑃<0.05 and **𝑃<0.01 compared with the HFD group.