The Antiobesity Effect of Polygonum aviculare L. Ethanol Extract in High-Fat Diet-Induced Obese Mice

Table 3

The effects of PAE on blood parameters in HFD-fed obese mice.

	ND	HFD	HFD + PAE	HFD + Orlistat	HFD + BPT
Total cholesterol, mg/dL	121±2.6	161±2.7^###	157 ± 4.2	147±4.1 *	151±7.8
Triglyceride, mg/dL	68±23.3	83±4.5^##	53 ± 5.9*	76±9.8	51±4.9 **
LDL-cholesterol, mg/dL	4.2±0.5	4.8±0.3	5.2 ± 0.3	4.7±0.2	5.8±0.6
HDL-cholesterol, mg/dL	64.4±1.9	66.6±1.0	68.6 ± 1.4	68.2±2.3	65.9±3.0
ALT, U/L	46.4±2.5	35.0±9.9	23.3 ± 1.8	25.4±1.9	24.7±0.5
AST, U/L	81.2±11.6	141.5±19.3^#	62.5 ± 8.2*	80.0±11.9	55.1±3.1 *
BUN, mg/dL	31.6±1.1	21.4±1.3^###	22.4 ± 1.2	20.1±1.1	21.0±1.2
Creatinine, mg/dL	0.45±0.0	0.41±0.0	0.44 ± 0.0	0.43±0.0	0.48±0.0
Leptin, ng/mL	4.09±0.6	19.40±3.2^###	8.88 ± 0.9*	9.17±0.9 *	10.87±2.8
Adiponectin, 𝜇g/mL	12.27±0.5	13.43±0.4	12.85 ± 0.5	11.51±0.9	12.85±0.5

Values are expressed as means ± SEM (n = 5–7).
^#𝑃<0.05, ^##𝑃<0.01 and ^###𝑃<0.001 compared with the ND group. *𝑃<0.05 and **𝑃<0.01 compared with the HFD group.