Subamolide B Isolated from Medicinal Plant Cinnamomum subavenium Induces Cytotoxicity in Human Cutaneous Squamous Cell Carcinoma Cells through Mitochondrial and CHOP-Dependent Cell Death Pathways

Table 1

IC^∗₅₀ (𝜇M) of subamolide B for human cell lines examined in this study.

Skin cancer cell lines				Normal skin fibroblasts		Normal lung fibroblasts
A375	A-431	BCC-1	SCC12	CCD-966SK	WS1	IMR-90	MRC-5	WI-38
17.59	13.30	>20	9.12	>20	>20	>20	>20	>20

 *IC₅₀ is defined as the dosage of subamolide B capable to reduce cell viability by 50% after 48 h treatment.