Hepatoprotective Activity of Methanolic Extract of Bauhinia purpurea Leaves against Paracetamol-Induced Hepatic Damage in Rats

Table 2

Effect of MEBP on percentage change of body and liver weight in PCM-treated rats.

Treatment	Dose (mg/kg)	Change of body weight (%)	Liver weight (g/100 g)
Control	—	5.14 ± 0.43	2.89 ± 0.06
PCM		17.58 ± 2.10^a	4.81 ± 0.40^a
Silymarin + PCM	200	3.11 ± 0.67^b	3.60 ± 0.11^b
MEBP + PCM	50	15.57 ± 1.53^a	5.66 ± 0.39^a
	250	11.07 ± 0.73^ab	4.29 ± 0.17^a
	500	4.55 ± 0.91^b	4.06 ± 0.24^ab

Values are expressed as means ± S.E.M. of six replicates.
aData differed significantly (𝑃<0.05) when compared to normal control within the respective column.
bData differed significantly (𝑃<0.05) when compared to the negative control within the respective column.