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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 639083, 10 pages
http://dx.doi.org/10.1155/2013/639083
Research Article

Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein

1Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China
2New Drug Research and Development Centre of North China Pharmaceutical Group Corporation, Hebei 050015, China
3College of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China
4College of Pharmaceutical Science, Hebei University, Baoding, Hebei 071002, China
5China Academy of Chinese Medical Sciences, Beijing 100700, China

Received 16 May 2013; Accepted 24 June 2013

Academic Editor: Shun-Fa Yang

Copyright © 2013 Chang Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

In order to identify the molecular structure of coniferyl ferulate (CF), the mass spectrum [TOF-MS spectra (ES+ and ES-) of CF] and nuclear magnetic resonance spectroscopy [1H-NMR spectrum (500 MHz) of CF in CDCl3 and 13C-NMR spectrum (125 MHz) of CF in CDCl3] had been provided as the supporting information.

  1. Supplementary Materials