Evaluation of a Propolis Water Extract Using a Reliable RP-HPLC Methodology and In Vitro and In Vivo Efficacy and Safety Characterisation

Table 2

Results of linearity, quantitation, and detection limits determined for the five phenolic compounds used in this study.

Chemical marker	Regression curve	𝑟	LOD; 𝜇g/mL	LOQ; 𝜇g/mL
Caffeic acid	𝑦=0.0417𝑥−0.0136	0.9991	0.39	1.51
p-coumaric acid	𝑦=0.0752𝑥−0.0891	0.9993	0.21	0.81
trans-cinnamic acid	𝑦=0.1547𝑥−0.0148	0.9993	0.10	0.40
Aromadendrin	𝑦=0.0322𝑥−0.0154	0.9992	0.52	2.00
Artepillin C	𝑦=0.0221𝑥−0.0562	0.9992	0.50	1.93