Protective Role of Psoralea corylifolia L. Seed Extract against Hepatic Mitochondrial Dysfunction Induced by Oxidative Stress or Aging
Figure 1
Effects of the PCS extract on senescent HDF cells. (a) HDF cells were treated with PCS extract (100 μg/mL) or water as a control (CON) for 24, 48, or 72 h. Cell viability was measured by a CCK-8 assay kit. (b) HDF cells were treated without (−) or with the PCS extract (50 μg/mL) for 24 h. mRNA for was analyzed by qRT-PCR. (c) HDF cells were treated without (−) or with the PCS extract (50 μg/mL) for 72 h and incubated for 48 h in normal media. SA-β-gal was detected using a Senescence Detection Kit. “Young,” less than 13 passages, “old,” more than 32 passages. Resveratrol (Res, 50 μM) was used as a positive control. * versus (−)/old HDF cells.
