Salidroside Improves Homocysteine-Induced Endothelial Dysfunction by Reducing Oxidative Stress

Figure 1

(a) Representative traces showing the impaired endothelium-dependent relaxations (EDR) by 45 min treatment with 300 μM homocysteine (Hcy) and the restoration of EDR by salidroside in rat aortas. The cumulative concentration-response curves for ACh-induced relaxations under treatment with two concentrations of salidroside (b) and with tiron or DPI (c) in Hcy-treated rat aortas. Results are means ± SEM of 6-7 separate experiments. *𝑃<0.05 versus control; ^#𝑃<0.05 versus Hcy.

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