Figure 8: Effect of girinimbine on activation of caspases 3/7, 8, and 9. Cells were treated with girinimbine at the indicated concentrations for 24 h and activity was determined by using a luminescent enzyme assay kit. Each point represents the mean ± SD of three different experiments. Statistical analysis was performed with one-way analysis of variance (ANOVA) using GraphPad Prism software (version 4.0; GraphPad Software Inc., San Diego, CA). Statistical significance is expressed as ; .