Ameliorative Effects of Acanthopanax trifoliatus on Cognitive and Emotional Deficits in Olfactory Bulbectomized Mice: An Animal Model of Depression and Cognitive Deficits
Separation of phenolics and flavonoids in A. trifoliatus leaf extract by HPLC; peak 1 = chlorogenic acid, peak 2 = 3,5-di-O-caffeoylquinic acid, peak 3 = rutin and isoquercetin, peak 4 = 4,5-di-O-caffeoylquinic acid, and peak 5 = quercitrin. Column: X-terra C18. Gradient mobile phase: water/0.5% acetic acid (solvent A) and methanol (solvent B). Detector: UV detector at 310 nm.