Research Article

Methanolic Extracts of Bitter Melon Inhibit Colon Cancer Stem Cells by Affecting Energy Homeostasis and Autophagy

Figure 2

Bitter melon extracts cause S and G2/M cell cycle arrest. (a) Cell cycle analyses of bitter melon extract treated cells. HT-29 and SW480 cells were treated with 150 μg/mL of bitter melon extract for 24 h, and subsequently examined by flow cytometry following propidium iodide staining for DNA content. Graphs are representative of data collected from three experiments. (b) Tabular representation of HT-29 and SW480 cells treated with 0 to 150 μg/mL of bitter melon extract for 24 h.
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