Does Oral Ingestion of Piper sarmentosum Cause Toxicity in Experimental Animals?

Figure 3

The histology of liver cells with H&E staining method of rats treated with 50 mg/kg, 300 mg/kg, and 2000 mg/kg of Piper sarmentosum aqueous extract and normal saline for 28 consecutive days at 50 and 200 times magnification. There were no significant changes showing congestion or destruction of liver cells observed in the histological section of the liver tissues of the treatment groups compared to the control group. PT: portal triad; PV: portal vein; He: hepatocyte; S: sinusoid; A: hepatic artery; D: bile duct.