Research Article

In Vivo Immunomodulation and Lipid Peroxidation Activities Contributed to Chemoprevention Effects of Fermented Mung Bean against Breast Cancer

Table 1

Body weight (g) and tumor volume (mm3) changes after inoculation of 4T1 cell up to day 21. Each value represents the means ± S.D. for six mice in triplicate each. The differences between the control or treated group and untreated group were determined by one-way ANOVA.

Body weight (g)Tumor volume (mm3)
Day 0Day 7Day 14Day 21Day 7Day 14Day 21

Group 1 *a *a
Group 2
Group 3
Group 4 * * *
Group 5 a a a a
Group 6 * * *
Group 7 a
Group 8 * * *
Group 9 a a a a

Group 1: normal mice; Group 2: untreated 1 × 104 4T1 cell (low risk) inoculated mice; Group 3: untreated 1 × 106 4T1 cell (high risk) mice; Group 4: tamoxifen (1 mg/kg b.w.) treated 1 × 104 4T1 cell (low risk) inoculated mice; Group 5: tamoxifen (1 mg/kg b.w.) treated 1 × 106 4T1 cell (high risk) inoculated mice; Group 6: fermented mung bean (200 mg/kg b.w.) treated 1 × 104 4T1 cell (low risk) inoculated mice; Group 7: fermnted mung bean (200 mg/kg b.w.) treated 1 × 106 4T1 cell (high risk) inoculated mice; Group 8: fermented mung bean (1000 mg/kg b.w.) treated 1 × 104 4T1 cell (low risk) inoculated mice; Group 9: fermented mung bean (1000 mg/kg b.w.) treated 1 × 106 4T1 cell (high risk) inoculated mice.
*For low risk groups while afor high risk groups; .