Kai-Xin-San, a Chinese Herbal Decoction Containing Ginseng Radix et Rhizoma, Polygalae Radix, Acori Tatarinowii Rhizoma, and Poria, Stimulates the Expression and Secretion of Neurotrophic Factors in Cultured Astrocytes
Figure 4
The comparison of KXS and single herb in stimulating the secretion of neurotrophic factors in astrocytes. Astrocytes were treated with DZW-652 (15 μg/mL), the extract of Ginseng Radix et Rhizoma (4.5 μg/mL), the extract of Polygalae Radix (3 μg/mL), the extract of Acori Tatarinowii Rhizoma (3 μg/mL), and the extract of Poria (4.5 μg/mL) for 48 hours, and then the media were collected to determine the amount of NGF, BDNF, and GDNF. Data are expressed as percentage of increase to control (no drug treatment, that is, 0 extract here). Values are showed as the Mean ± SEM, . Abbreviations: GR: Ginseng Radix et Rhizoma; PR: Polygalae Radix; ATR: Acori Tatarinowii Rhizoma; PO: Poria.
