Chinese Herbal Medicine for Acute Mountain Sickness: A Systematic Review of Randomized Controlled Trials

Table 1

Clinical trials of Chinese herbal interventions in treating AMS with a concomitant population.

Reference (year)	Study design	Participants T/C	Intervention; (herbs included)	Control	Outcome measure	Treatment duration (days)
Chen et al. (2006) [29]	RCT	23/23	Fufang yi hao pill; (3 pills, tid)	Placebo; (3 pills, tid)	Score of AMS	7
Song et al. (2011) [30]	RCT	18/18	Sheng nao kang pill; (10 pills, tid)	Placebo; (10 pills, tid)	Score of AMS	10
Tang et al. (2013) [31]	RCT	26/15	Sheng nao kang pill; (10 pills, tid)	Placebo; (10 pills, tid)	Score of AMS	7
Niu et al. (2006) [32]	RCT	50/50	Shu li kang capsule; (3 pills, bid)	Placebo; (3 pills, bid)	Score of AMS	7
Li et al. (2008) [33]	RCT	9/19	Root of Rhodiola rosea; (15 g, qd)	No drug	Score of AMS	7 d
Zhang et al. (2003) [34]	RCT	20/18	Ginkgo leaf tablet (2 pills, bid)	Acetazolamide (125 mg, bid)	Score of AMS	7
Zhang et al. (2010) [35]	RCT	30/15	New compound, rhodiola pill (2 pills, qd)	Acetazolamide; (125 mg, bid)	Score of AMS	5
Fang (2008) [36]	RCT	40/38	Xing nao jing injection (20 mL, ivgtt, qd) plus routine treatment	Routine treatment	Score of AMS	3
Fang (2011) [37]	RCT	39/37	Danhong injection (20 mL, ivgtt) plus routine treatment	Routine treatment	Score of AMS	5

Bid: twice daily; tid: three times daily; qd: four times daily; T/C: treatment group and control group; CT: clinical trial; RCT: randomized clinical trial; NR: not reported.