Hepatoprotective Role of Ethanolic Extract of Vitex negundo in Thioacetamide-Induced Liver Fibrosis in Male Rats

Table 2

Body weight and liver and spleen weights of the rats in different groups.

Group	Body weight (g)	Liver weight (g)	Liver index (%)	Spleen weight (g)	Spleen index (%)
Normal	219.8±29.88^b	6.78±0.71^b	3.13±0.51^b	0.495±0.08^b	0.227±0.03^b
TAA	177.5±7.1^a	8.27±0.99^a	4.66±0.57^a	0.863±0.13^a	0.488±0.08^a
VN 300	226.16±22.62^b	6.78±0.69^b	3.46±0.85^b	0.647±0.12^b	0.287±0.05^b
VN 100	221.15±15.91^b	6.69±0.55^b	3.04±0.38^b	0.643±0.68^b	0.24±0.12^b
VN 300 + TAA	204.3±10.70	6.9±0.67^b	3.39±0.40^b	0.641±0.07^b	0.313±0.03^b
VN 100 + TAA	199.3±15.98	7.2±0.27	3.64±0.39^b	0.588±0.10^b	0.295±0.06^b
SY + TAA	210.16±12.05	7.03±0.40	3.34±0.09^b	0.602±0.15^b	0.23±0.031^b

The data were stated as mean ± SEM. Means with different superscripts are significantly different. ^a𝑃<0.05 versus normal control group and ^b𝑃<0.05 versus TAA group. SY stands for Silymarin (standard hepatoprotective drug).