Research Article

Antimalarial Activity of Cocos nucifera Husk Fibre: Further Studies

Table 3

Parasitaemia in P. berghei NK65-infected mice treated with ethyl acetate fraction of Cocos nucifera (West African Tall variety) husk fibre extract.

Groups (dose in mg/kg b.w.)Parasitaemia (% reduction)
10°

Untreated control2.85 5.716.43 9.48
31.25 1.42 (50.2)2.48 (56.6)5.20 (19.1)7.80 (17.7)
62.5 0.07 (97.5)1.52 (73.4)0.75 (88.3)3.58 (62.2)
125 0.04 (98.6)1.65 (71.1)0.88 (86.3)2.49 (73.7)
250 2.02 (29.1)2.00 (64.9)1.52 (76.4)1.60 (83.1)
500 0.37 (87.0)0.68 (88.1)0.15 (97.7)1.21 (87.2)
Chloroquine (20)0.04 (98.6)1.23 (78.5)0.65 (89.95)0.23 (97.6)

Values are means ± SD of 5 replicates. °Days after inoculation.