Immunosuppression of the Trimellitic Anhydride-Induced Th2 Response by Novel Nonanatural Products Mixture in Mice

Table 3

IC₅₀ of NPM-9 for IL-4 and IFN-γ.

Sample extract	IC50 for IL-4 (ug/mL)	Ratio of IFN-γ/IL-4
Licorice	62.7	3.00
Hawkweed	208	0.15
Beefsteak plant	213	0.10
Fenugreek	15.4	2.50
Skullcap	86.7	0.98
Black pepper	31.3	1.45
Green tea	80.3	0.23
Turmeric	148	0.15
Fermented soybeans paste (cheonggukjang)	54.3	0.82
NPM-9	12.7	4.80

IC₅₀ of IFN-γ and IL-4 were quantified by ELISA after cells were cultured for 72 h with splenocytes from OVA-induced allergic mice in the presence of each extract or NPM-9, Natural Nonaproduct Mixture.