Baicalein, Ethyl Acetate, and Chloroform Extracts of Scutellaria baicalensis Inhibit the Neuraminidase Activity of Pandemic 2009 H1N1 and Seasonal Influenza A Viruses

Table 2

Plaque reduction of influenza A virus by MeOH, EtOAc, and chloroform extracts of S. baicalensis.

Extracts	CC50 (μg/mL)	Plaque inhibition IC50 values (μg/mL)		Therapeutic index
	MDCK cells	Seasonal 2007 H1N1	Pandemic 2009 H1N1	Seasonal 2007 H1N1	Pandemic 2009 H1N1
MeOH	923.12 ± 0.017	134.22 ± 0.059	28.24 ± 0.049	6.9	32.7
EtOAc	836.24 ± 0.023	23.70 ± 0.053	27.39 ± 0.049	35.3	30.5
Chloroform	829.77 ± 0.009	41.49 ± 0.052	14.16 ± 0.083	20.0	58.6