Prunus mume and Lithospermum erythrorhizon Extracts Synergistically Prevent Visceral Adiposity by Improving Energy Metabolism through Potentiating Hypothalamic Leptin and Insulin Signalling in Ovariectomized Rats

Table 2

The parameters of indirect calorimetry at the end of experiment.

	Control (𝑛=15)	PMA (𝑛=15)	LES (𝑛=15)	PMA+LES (𝑛=15)	Sham (𝑛=15)
Energy expenditure (kcal/kg^0.75/day)	113.5±14.8^b	121.8±14.4^ab	128.8±14.7^a	139.6±15.1^a∗	137.0±14.8^†
Respiratory quotient	0.86±0.10	0.84±0.09	0.85±0.09	0.82±0.09	0.81±0.09
VO2 (mL/kg^0.75/min)	16.2±1.9^c	17.4±2.0^b	18.4±2.1^b	19.9±2.2^a∗	19.6±2.1^†
VCO2 (mL/kg^0.75/min)	14.0±1.7	14.6±1.8	15.6±1.9	16.3±1.9	15.9±1.8
Carbohydrate oxidation (mg/kg^0.75/min)	6.4±0.9	5.8±0.8	6.6±0.9	5.8±0.8	5.1±0.8^†
Fat oxidation (mg/kg^0.75/min)	5.5±0.8^c	7.1±1.0^b	7.1±1.0^b	9.1±1.4^a∗	9.5±1.2^†

Control, OVX rats fed a high fat diet (HFD) with 5% cellulose; PMA, OVX rats fed HFD with 5% Prunus mume;LES, OVX rats fed HFD 5% Lithospermum erythrorhizon; PMA+LES, OVX rats fed HFD with 2.5% PMA and 2.5% LES. Sham, Sham rats fed a high fat diet (HFD) with 5% cellulose.
*Significantly different among the groups of OVX rats at 𝑃<0.05.
^a,b,cValues on the same row with different superscripts were significantly different at 𝑃<0.05.
^†Significant difference between OVX rats and Sham rats at 𝑃<0.05.