Additive Complex Ayurvedic Treatment in Patients with Fibromyalgia Syndrome Compared to Conventional Standard Care Alone: A Nonrandomized Controlled Clinical Pilot Study (KAFA Trial)
Table 2
Outcomes in both groups at baseline, week 2 and month 6 with group differences as indicators of change.
Integrative medicine group
Conv. rheumatology group
Mean difference
Mean diff. (95% CI)
Baseline ()
Visit 2 ()
Visit 3 ()
Baseline ()
Visit 2 ()
Visit 3 ()
1-2 (95% CI)
value
1–3 (95% CI)
value
FIQ score
1.30 (−6.00; 8.59)
0.72
2.97 (−6.26; 12.20)
0.51
Pain score (NRS)
0.89 (−0.87; 2.65)
0.31
2.08 (−0.52; 4.69)
0.11
Quality of sleep
0.09 (−2.52; 2.70)
0.94
0.17 (−2.99; 3.33)
0.91
HADS anxiety
2.09 (−0.66; 4.84)
0.13
1.48 (−2.05; 5.00)
0.40
HADS depression
2.86 (0.67; 5.05)
0.01
2.43 (−0.37; 5.22)
0.09
SES sensory pain perception
0.61 (−4.73; 5.95)
0.82
2.72 (−3.97; 9.40)
0.41
SES affective pain perception
4.61 (−0.15; 9.38)
0.06
0.87 (−5.06; 6.80)
0.76
STAI state score
−0.44 (−9.75; 8.87)
0.92
7.97 (−0.19; 16.13)
0.06
STAI trait score
4.40 (−4.14; 12.93)
0.30
6.44 (−7.08; 19.95)
0.33
Values are mean ± SD if not indicated otherwise. SBP: systolic blood pressure; DBP: diastolic blood pressure. STAI: state and trait anxiety questionnaire, FIQ: fibromyalgia impact questionnaire; NRS: numeric rating scale 0–10; HADS: hospital anxiety and depression scale; 1-2: difference between groups from baseline to visit 2 at 2 weeks, 1–3: difference between groups from baseline to visit 3 at 12 weeks. SES: pain perception scale. values for between-group difference of change are adjusted.
