Ethanolic Extract of Polish Propolis: Chemical Composition and TRAIL-R2 Death Receptor Targeting Apoptotic Activity against Prostate Cancer Cells

Figure 7

Effects of EEP-P on death receptor expression in LNCaP prostate cancer cells. Cells were incubated with 25–50 μg/mL for 12–24 h. (a) TRAIL-R1 and (b) TRAIL-R2 expression on LNCaP cells treated with EEP-P measured by flow cytometry. The values represent mean ± SD of three independent experiments performed in quadruplicate (𝑛=12) shown as the average mean fluorescence (^∗∗∗=𝑃<0.001 EEP-P compared to isotype control, ⁺⁺⁺=𝑃<0.001 EEP-P compared to control) and histograms.

(a)

(b)