Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Tab 1

Research Article

Ethanolic Extract of Polish Propolis: Chemical Composition and TRAIL-R2 Death Receptor Targeting Apoptotic Activity against Prostate Cancer Cells

Table 1

The content (mg/g) and characterization of phenolic compounds of the ethanol extract of Polish propolis determined using their spectral characteristic in negative ions in LC-ESI/MS.

PeakRetention time (min)(M−H)MS/MS fragmentsCompound name*Quantity (mg/g of propolis)**

12.26179.0349161.0241/135.0440Caffeic acida3.90
22.53121.0288121.0288Benzoic acidbc0.86d
32.69237.0772163.0406/145.0284/117.0342NiTr
42.79163.0406119.0488 -Coumaric acida28.65
52.88267.0899160.0154/133.0276NiTr
63.01193.0492178.0258/149.0613/134.0375Ferulic acida22.01
73.18357.0989279.0655/147.0441Ferulic acid derivativec0.59e
83.31295.0815161.0241/133.0299Ferulic acid derivativecTr
93.57359.1129163.0380/145.0284/119.0510Coumaric acid derivativec0.16g
103.72389.1221193.0492/134.0375/175.0399/160.0154Ferulic acid derivativec0.75e
113.88279.086145.0284/117.0342NiTr
124.15415.1065253.0730/179.0349/161.0241/135.0440Caffeic acid derivativec0.11f
134.27355.1176179.0349/163.0380/135.0440/119.0488Caffeic and coumaric acids derivativecTr
144.61399.1051253.0697/179.0349/163.0380/119.0488Coumaric and caffeic acids derivativec1.83g
154.70429.1214253.0697/193.0492/161.0241/134.0375Ferulic acid derivativec2.12e
164.86269.0469151.0042/117.0342Apigenina1.98
174.96383.1137Coumaric acid derivativec3.97g
185.05271.0616253.0502/197.0596/161.0605/125.0241/107.0134Pinobanksina12.78
195.10383.1137163.0406/119.0510Coumaric acid derivativec22.87g
205.20413.1240193.0492/163.0380/134.0375/119.0488Coumaric and ferulic acids derivative (metoxy-)c13.44e
215.27443.1320193.0492/163.0380/134.0375/119.0488Coumaric and ferulic acids derivative (dimetoxy-)c3.98e
225.44259.1917193.0492/163.0380/134.0375/119.0489Ferulic acid derivativec2.02e
235.63283.0594193.0492/134.0375Ferulic acid derivativec0.3e
245.73441.1179179.0349/163.0406/135.0440/119.0388Caffeic and coumaric acids derivativecTr
255.79315.0512121.0288Rhamnetina0.49
265.86471.1305297.1136/193.0492NiTr
276.25425.1242163.0406/119.0510Coumaric acid derivativec5.00
286.32247.0982179.0349/163.0380/135.0440Coumaric and caffeic acids derivativec0.31f
296.35253.0502143.0510Chrysina6.56
306.41269.0804178.0258/163.0380/134.0375/119.0488Ni
316.56269.0435171.0446/151.0042/117.0342Galangina0.47
326.56299.0572KaempferidegTr
336.66313.0745253.0502Pinobanksin-3-O-acetatebTr
346.94249.1131161.0241/133.0299Ni
357.13253.0860162.0308/151.0394/145.0284/117.0342Methoxyflavanonebc20.50h
367.25283.0973163.0380/145.0653/119.0488Coumaric acid derivativec10.49g
378.80449.2537361.2026/253.0502/121.0288Benzoic acid derivativec5.20d

Ni: not identified.
Tr: traces.
*a: confirmed by standard; b: confirmed by reference [41, 42]; c: confirmed by MS fragmentation.
**d: expressed as cinnamic acid; e: expressed as ferulic acid; f: expressed as caffeic acid; g: expressed as -coumaric acid; h: expressed as apigenin.