The Evaluation of the Body Weight Lowering Effects of Herbal Extract THI on Exercising Healthy Overweight Humans: A Randomized Double-Blind, Placebo-Controlled Trial
Table 3
Side effects during treatment of THI and placebo.
Side effects
THI
Placebo
value
()
()
Anorexia grade 1*
0
1 (4.3)
0.434
Nausea grade 1
5 (16.7)
1 (4.3)
0.217
Indigestion grade 1
8 (26.7)
3 (13.0)
0.313
Hunger pain grade 1
1 (3.3)
0
1.0
Abdominal pain grade 1
1 (3.3)
0
1.0
Loose stool grade 1
2 (6.7)
3 (13.0)
0.642
Diarrhea grade 1
4 (13.3)
1 (4.3)
0.374
Constipation grade 1
2 (6.7)
1 (4.3)
1.0
Facial edema grade 1
1 (3.3)
0
1.0
Headache grade 1
1 (3.3)
0
1.0
Insomnia grade 1
2 (6.7)
1 (4.3)
1.0
Itching grade 1
2 (6.7)
0
0.499
Fatigue grade 1
1 (3.3)
1 (4.3)
1.0
Palpitation grade 1
0
1 (4.3)
0.434
Satiety grade 1
2 (6.7)
2 (8.7)
1.0
Relieve constipation grade 1
5 (16.7)
4 (17.4)
1.0
Good appetite grade 1
1 (3.3)
1 (4.3)
1.0
Increased gastric acid secretion grade 1
1 (3.3)
0
1.0
Suppression of appetite grade 1
3 (10.0)
4 (17.4)
0.451
Thirst grade 1
1 (3.3)
0
1.0
Chi-square test; * value using Fisher’s exact test. Values given are number of patients (%). Grading scale of Common Terminology Criteria for Adverse Events v3.0 (CTCAE).
