Salvianolic Acid B Prevents Arsenic Trioxide-Induced Cardiotoxicity In Vivo and Enhances Its Anticancer Activity In Vitro

Figure 2

Effects of Sal B on ATO-induced myocardial injury in vivo. (a) Effects of Sal B on histological changes in mice hearts by HE (hematoxylin and eosin) staining (×200). (b) Effects of Sal B on the activities of CK, LDH, GOT, CAT, SOD, and GSH-PX in plasma. Values (𝑛=15 per group) are expressed as means ± SD. *𝑃<0.05 versus control; **𝑃<0.01 versus control; ^#𝑃<0.05 versus ATO-treated mice; ^##𝑃<0.01 versus ATO-treated mice. CK: creatine kinase; LDH: lactate dehydrogenase; GOT: glutamic oxaloacetic transaminase; CAT: catalase; SOD: superoxide dismutase; GSH-PX: glutathione peroxidase.

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