Exploring Antiurolithic Effects of Gokshuradi Polyherbal Ayurvedic Formulation in Ethylene-Glycol-Induced Urolithic Rats

Table 3

Effect of GPAE and standard drug on serum parameters.

Parameters	Control	Urolithic	GPAE 50 mg/kg	GPAE 100 mg	Standard drug 100 mg/kg
SC^c (mg/dL)	0.86 ± 0.05	1.43**  ± 0.12	1.26 ± 0.16	0.89^#  ± 0.10	1.08 ± 0.12
CC^d (mg/min)	0.86 ± 0.06	0.50**  ± 0.06	0.64 ± 0.10	0.85^##  ± 0.07	0.72 ± 0.12
BUN^e (mg/dL)	19.89 ± 1.40	57.04**  ± 12.46	46.3 ± 11.40	20.5^##  ± 1.08	36.2 ± 10.20

Values given are mean ± S.E.M. (n = 6).
* P < 0.05.
** P < 0.01 versus control group.
^#P < 0.05.
^##P < 0.01 versus urolithic group.
^cSerum creatinine. ^dCreatinine clearance. ^eBlood urea nitrogen.