Chinese Medicinal Formula (MHGWT) for Relieving Diabetic Neuropathic Pain: A Randomized, Double-Blind, Placebo-Controlled Trial

Table 2

Changes of scores of Short-Form Brief Pain Inventory questionnaire after interventions.

Domains	Group, number		𝑃 value
	MHGWT group (𝑛=56)	Placebo group (𝑛=56)
Sensory
Baseline	25.43 ± 8.13	21.45 ± 8.37	0.01^∗
Time 2  −  baseline	− 5.48 ± 6.70	0.20 ± 8.90	0.001^∗∗∗
Time 3 − baseline	− 12.62 ± 7.57	0.16 ± 8.19	<0.0001^∗∗∗
Time 4 − baseline	− 15.64 ± 8.78	0.53 ± 7.88	<0.0001^∗∗∗
Scheffe’s test for time effect	a > b > c > d
Daily life
Baseline	27.43 ± 12.25	23.34 ± 13.00	0.10
Time 2 − baseline	− 9.77 ± 9.10	0.32 ± 11.25	<0.0001^∗∗∗
Time 3 − baseline	− 15.14 ± 10.63	− 3.47 ± 13.84	<0.0001^∗∗∗
Time 4 − baseline	− 18.36 ± 11.66	− 4.66 ± 14.49	<0.0001^∗∗∗
Scheffe’s test for time effect	a > b > c, d	a > d

Time 2 was in the end of 4 weeks, time 3 was in the end of 8 weeks, and time 4 was in the end of 12 weeks.
Data were presented as mean ± SD.
𝑃 values are calculated for the comparison of difference between MHGWT and placebo groups by independent 𝑡-test.
^∗𝑃<0.05; ^∗∗∗𝑃<0.001.
a: time 1; b: time 2; c: time 3; d: time 4.