Scopoletin Inhibits Rat Aldose Reductase Activity and Cataractogenesis in Galactose-Fed Rats
Figure 3
Lens fiber changes. The lens sections from the normal rats (NOR), the vehicle-treated galactose-fed rats (GAL), the galactose-fed rats treated with scopoletin at concentration 10 mg/kg (SCO-10), and the galactose-fed rats treated with scopoletin at concentration 50 mg/kg (SCO-50) were labeled with rhodamine-conjugated wheat germ agglutinin. Fiber cell liquefaction, swelling, and membrane rupture were observed in galactosemic cataractous lens.
