Scopoletin Inhibits Rat Aldose Reductase Activity and Cataractogenesis in Galactose-Fed Rats

Figure 4

Polyol pathway. (a) Aldose reductase (AR) activity, (b) galactitol levels in lenses from the normal rats (NOR), the vehicle-treated galactose-fed rats (GAL), the galactose-fed rats treated with scopoletin at concentration 10 mg/kg (SCO-10), and the galactose-fed rats treated with scopoletin at concentration 50 mg/kg (SCO-50). All data are expressed as the means ± SE, 𝑛=10. ^#𝑃<0.01 versus normal control rats, *𝑃<0.01 versus vehicle-treated galactose-fed rats.

(a)

(b)