Achyrocline satureioides (Lam.) D.C. Hydroalcoholic Extract Inhibits Neutrophil Functions Related to Innate Host Defense
Figure 2
Effects of A. satureoides hydroalcoholic extract on in vivo leukocyte migration induced by LPS. Air pouch animals received orally: (1) vehicle (PBS/ethanol 10%), (2) indomethacin (30 mg/kg), or (3) A. satureoides (50, 100, or 250 mg/kg). LPSs from E. coli 026:B6 (1 mg/2 mL) or PBS were injected after 1 h directly into the air pouch, and 4 h later, the number of cells in the pouch was quantified. The dotted line indicates the number of neutrophils in the noninflamed tissue. (a) Number of total leukocytes in the air pouch. (b) Number of neutrophils in the air pouch. Data are expressed as mean ± S.E.M. of 5-6 animals in each group. Statistical analysis was performed using ANOVA followed by Tukey’s test. versus vehicle.
