Inclusion Complex of Zerumbone with Hydroxypropyl-<b><i>β</i></b>-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio

<table>Percentages of cell cycle distribution in sub-G0/G1 (apoptosis cells), G0/G1, S, and G2/M phase of HepG2 cells treated with 11.43 <i>μ</i>g/mL of ZER-HP<i>β</i>CD inclusion complex for 24, 48, and 72 h. Induction of G2/M arrest in cell cycle progression of HepG2 cells by ZER-HP<i>β</i>CD inclusion complex. <svg height="13.95" id="M32" style="vertical-align:-0.16379pt" version="1.1" viewbox="0 0 74.612503 13.95" width="74.612503" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) compared with control. </table>

Evidence-Based Complementary and Alternative Medicine

fig6

Figure 6

Figure 6: Inclusion Complex of Zerumbone with Hydroxypropyl-<b><i>β</i></b>-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio 

Figure 6 | Inclusion Complex of Zerumbone with Hydroxypropyl-β-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio 