| | Chalcones | Cell lines | Reference |
| | Butein (1) | HSC-2, HSC-3, HSG, HL-60 | [4] | | Flavokawain B (2) | T24, KB, HCT116 | [5] | | Flavokawain C (17) | T24, PANC-1 | [6, 7] | | Pinostrobin chalcone (3) | KB, MCF7, Caski, MRC5 | [5] | 2′,4′-dihydroxy-3,4-dimethoxychalcone (4),
2′,4′-dihydroxy-2,3-dimethoxychalcone (5),
2′,4′-dihydroxy-4-methoxychalcone (6) | HL-60, SMMC-7721 | [8] | | 2′,4′-dihydroxy-3′,5′-dimethyl-6′-methoxychalcone (7) | SMMC-7721, 8898, HeLa, SPC-A-1, 95-D, GBC-SD, MCF-7, SKBR-3, SW-480 | [9, 10] | | Stercurensin (8) | SW-480 | [11] | | Cardamonin (9) | SW-480, PANC-1 | [11] | | 2′,4′-dihydroxychalcone (10) | 26-L5, B16-BL6, LLC, A549, HeLa, HT-1080 | [12] | | 4,4′-dihydroxy-2′-methoxychalcone (11) | 26-L5, B16-BL6, LLC, A549, HeLa, HT-1080, SH-SY5Y | [12, 13] | | Isoliquiritigenin (12) | 26-L5, B16-BL6, LLC, A549, HeLa, HT-1080 | [12, 14] | 3′,4,4′-trihydroxy-2,6-dimethoxychalcone (15),
3′,6-dihydroxy-2,4,4′-trimethoxy-3-(3′′,4′′-dihydroxybenzyl)chalcone (95) | MCF-7/ADR, BEL-7402/5-FU | [15] | | 3′-formyl-2′,4′-dihydroxy-6′-methoxychalcone (20) | KB, MCF-7 | [16] | | Abyssinone A (50), B (51), C (52), D (27) | Caco2 | [17] | | 5′′-(2′′′-hydroxyisopropyl-)-dihydrofurano-[2′′,3′′-B]-4,4′-dihydroxy-6′-methoxychalcone (67) | BGC-823 | [18] | Flavokawin (13),
3′-geranylchalconaringenin (29),
5′-prenylxanthohumol (30),
xanthohumol H (31), xanthogalenol (33),
4-methylxanthohumol (34),
xanthohumol C (53),
1′′,2′′-dihydroxanthohumol C (55) | HeLa | [19] | | Desmethylxanthohumol (32) | HeLa, DU145, PC-3 | [20, 21] | | Licochalcone A (35), C (36), E (37) | HT-1080 | [14] | | 2′,4′,2,4-tetrahydroxy-3′-prenyl-6′-methoxychalcone (38) | HL-60, L1210, U937 | [22] | | Cyclokuraridin (58) | KB | [23] | | 3-hydroxy-4-methoxylonchocarpin (60) | A2780, B16, K562, LL/2, 7860, HeLa | [24] | | 4-methoxylonchocarpin (61) | HeLa, K562, LL/2, 7860, A2780, B16 | [24] | | Isobavachromene (62) | 7860, A549, A2780, B16, HeLa, K562, LL2 | [24] | | Millepachine (66) | HepG2, C26, LL2, B16 | [25] | | 5′-geranyl-2′,4′,4-trihydroxychalcone (39) | SW 872, HT-29, Hep3B, PLC5, Huh7, HepG2, COLO205 | [26] | | Isocordoin (40) | P388 | [27] | Derricin (41),
lonchocarpin (59) | CEM | [28] | | Isobavachalcone (42) | HT-1080, MCF-7, MCF-7/ADR | [29] | | 4-hydroxyderricin (47) | KATO III | [30] | | Xanthoangelol (44) | SW 872, HT-29, COLO205, Hep3B, PLC5, Huh7, HepG2, KATO III | [26, 30] | | Isolespeol (68) | HT-29, COLO205, Hep3B, PLC5, Huh7 | [26] | 2′,4′-dihydroxy-3′-(1′′-geranyl)-6′-methoxychalcone (28), (−)-nicolaioidesin B (71),
(±)-isopanduratin A1 (72),
(1′R,2′S,6′R)-2-hydroxyisopanduratin A (73),
panduratin A (74), (−)-isopanduratin A2 (75),
(−)-hydroxypanduratin A (76),
(±)-panduratin C (77),
(±)-6-methoxypanduratin A (78), | PANC-1 | [7] | |
Australisine A (85) | HCT-8, A2780 | [31] | | Australisine B (79), mulberrofurans E (80), F (81), mongolicin C (83), chalcomoracin (84) | A549, Bel7402, BGC-823, HCT-8, A2780 | [31] | | Mulberrofuran G (82) | A549, BGC-823, HCT-8, A2780 | [31] | | Australisine C (86) | A2780 | [31] | | Yunanensin A (87) | A549, Bel7402, BGC-823, HCT-8, A2780 | [32] | | Japonicone A (94) | HeLa, Bel7402, MCF-7/ADR, Bel7402/5-FU | [33] | | 3′,6-dihydroxy-2,4,4′-trimethoxy-3-(3′′,4′′-dihydroxybenzyl)chalcone (95) | MCF-7/ADR, BEL-7402/5-FU | [15] | | 2′,4′-dihydroxy-3′-(2-hydroxybenzyl)-6′-methoxychalcone (96) | KB, BC | [34] | | Rhuschalcones I (23), II (24), III (25), V (97), VI (98) | HT-29, HCT-116 | [35] | | Rhuschalcone IV (26) | HT-29, HCT-116, SK-MEL-5, SK-MEL-28, UACC-62 | [35] | | Xanthohumol (49) | DU145, PC-3, HeLa, MCF-7/ADR, HT-1080 | [19–21, 29] |
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