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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 818709, 11 pages
http://dx.doi.org/10.1155/2013/818709
Research Article

Integration of Different “-omics” Technologies Identifies Inhibition of the IGF1R-Akt-mTOR Signaling Cascade Involved in the Cytotoxic Effect of Shikonin against Leukemia Cells

1Institute of Pharmacy and Biochemistry, Department of Pharmaceutical Biology, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany
2Agricultural Biotechnology Research Center, Academia Sinica, 115 Taipei, Taiwan
3Cytometry Core Facility, Institute of Molecular Biology, Ackermannweg 4, 55128 Mainz, Germany
4HanseMerkur Center for Traditional Chinese Medicine at the University Medical Center Eppendorf, 20246 Hamburg, Germany

Received 18 March 2013; Accepted 7 May 2013

Academic Editor: Sookyung Lee

Copyright © 2013 Benjamin Wiench et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Benjamin Wiench, Yet-Ran Chen, Malte Paulsen, et al., “Integration of Different “-omics” Technologies Identifies Inhibition of the IGF1R-Akt-mTOR Signaling Cascade Involved in the Cytotoxic Effect of Shikonin against Leukemia Cells,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 818709, 11 pages, 2013. https://doi.org/10.1155/2013/818709.