Table 3: The change of 7 types of strains numbers, Firmicutes/Bacteroidetes ratio in feces, and IPI value among 4 groups between 0 week and 8 weeks.

VariablesGJS-P+DUO-P
( )
GJS+DUO-P
( )
GJS-P+DUO
( )
GJS+DUO
( )
P value

log10 (Mean ± SD)/1 g feces of bacterial speciesB. longum 0.695
B. brevis <0.001
B. lactis <0.001
S. thermophilus 0.01
L. rhamnosus <0.001
L. plantarum <0.001
L. acidophilus <0.001
Firmicute/Bacteriodetes 0.211

The change of IPI value 0.398

GJS: Gwakhyangjeonggisan, DUO: Duolac7S, GJS-P: placebo of Gwakhyangjeonggisan, DUO-P: placebo of Duolac7S, IPI (%): intestinal permeability index (Lactulose/mannitol).
The change of number of bacterial species was analyzed by one way-ANOVA and presented as log10 (mean ± SD)/1 g feces.
The change of intestinal permeability index is presented as percentage (%).