In Vitro Antimicrobial Activity of Extracts from Plants Used Traditionally in South Africa to Treat Tuberculosis and Related Symptoms

Table 2

The antibacterial (MIC values) effects of plants used traditionally as remedies for the treatment of tuberculosis and related symptoms in South Africa.

Plant species	Plant part	Extract	Extract yield % (DW)	Antibacterial activity MIC (mg/mL)
				Klebsiella pneumoniae	Mycobacterium aurum A+	Staphylococcus aureus
A. precatorius subsp. africanus	L	PE	1.03	12.50	12.50	12.50
		DCM	1.24	12.50	0.78	12.50
		80% EtOH	3.54	3.13	0.195	1.56
		Water	2.66	6.25	12.50	3.13
	S	PE	2.28	12.50	12.50	6.25
		DCM	2.87	12.50	6.25	3.13
		80% EtOH	3.42	6.25	0.78	1.56
		Water	2.43	1.56	1.56	3.13
A. africanus	L	PE	0.40	12.50	6.25	12.50
		DCM	0.50	12.50	6.25	12.50
		80% EtOH	1.50	6.25	0.39	6.25
		Water	6.80	1.56	6.25	12.50
A. falcatus	L	PE	0.80	12.50	3.13	12.50
		DCM	0.62	12.50	1.56	12.50
		80% EtOH	2.76	6.25	0.39	3.13
		Water	1.00	3.13	2.56	1.56
B. grandiflora	Bb	PE	2.83	12.50	12.50	12.50
		DCM	0.98	12.50	3.13	6.25
		80% EtOH	4.47	3.13	3.13	6.25
		Water	3.42	3.13	3.13	6.25
F. sur	B	PE	0.50	12.50	6.25	12.50
		DCM	0.50	12.50	6.35	12.50
		80% EtOH	0.60	6.25	3.13	6.25
		Water	0.40	6.25	6.25	12.50
	R	PE	3.20	6.25	12.5	12.50
		DCM	0.70	6.25	6.25	12.50
		80% EtOH	7.70	0.78	3.13	0.195
		Water	2.10	12.50	3.13	3.13
I. arrecta	L	PE	2.66	6.25	12.50	12.50
		DCM	1.79	12.50	6.25	12.50
		80% EtOH	11.15	0.78	0.39	0.39
		Water	9.69	12.50	0.78	6.25
	R	PE	0.60	12.50	6.25	12.50
		DCM	0.70	12.50	1.56	12.50
		80% EtOH	11.40	3.13	1.56	1.56
		Water	0.80	6.35	12.50	12.50
L. intermedia	L	PE	1.02	12.50	6.25	12.50
		DCM	1.00	12.50	12.50	12.50
		80% EtOH	5.62	6.25	0.195	0.78
		Water	3.20	3.13	3.13	1.56
	St	PE	0.50	6.25	3.13	12.50
		DCM	0.60	6.25	12.50	12.50
		80% EtOH	4.80	3.13	1.56	1.56
		Water	3.00	3.13	1.56	6.25
P. prunelloides	L	PE	1.30	6.25	6.25	12.50
		DCM	1.40	12.50	12.50	6.25
		80% EtOH	4.40	3.13	0.39	0.195
		Water	1.50	3.13	1.56	0.39
	R	PE	0.20	6.25	3.13	12.50
		DCM	0.20	6.25	12.50	12.50
		80% EtOH	11.40	0.39	0.78	0.78
		Water	6.76	1.56	1.56	1.56
P. fruticosa	Wp	PE	0.73	6.25	1.56	6.25
		DCM	1.04	6.25	1.56	6.25
		80% EtOH	16.67	3.13	3.13	1.56
		Water	4.84	3.13	3.13	6.25
T. phanerophlebia	L	PE	0.50	6.25	6.25	6.25
		DCM	1.20	6.25	6.25	6.25
		80% EtOH	16.00	0.195	1.56	0.195
		Water	9.80	0.39	0.39	0.098
	R	PE	0.10	12.50	6.25	12.50
		DCM	0.30	6.25	3.13	6.25
		80% EtOH	12.90	1.56	3.13	0.195
		Water	1.70	3.13	6.25	0.39
	T	PE	1.00	6.25	3.13	6.25
		DCM	0.40	6.25	1.56	3.13
		80% EtOH	11.00	0.195	0.195	0.39
		Water	3.70	1.56	1.56	1.56
Neomycin				0.0975		0.0975
Streptomycin					0.195

L: leaves, R: roots, B: bark, Bb: bulb, S: seeds, St: stem, Wp: whole plant, T: twigs, MIC: minimum inhibitory concentration, DCM: dichloromethane, PE: petroleum ether, EtOH: ethanol, % DW: percentage dry weight Values boldly written are considered very active.