Research Article

Acute and Chronic Toxicity of an Aqueous Fraction of the Stem Bark of Stryphnodendron adstringens (Barbatimão) in Rodents

Table 4

Biochemical parameters in male and female rats orally treated with F2 of S. adstringens for 90 days.

ParametersControlsF2 (mg·kg−1)
10100200

Male
Sodium (mEq·L−1)
Potassium (mEq·L−1)
Glucose (mg·dL−1)
Triglyceride (mg·dL−1)
Cholesterol (mg·dL−1)
Uric acid (mg·dL−1)
ALP (U·L−1)
AST (U·L−1)
ALT (U·L−1)
Total protein (g/dL)
Total bilirubin (mg·dL−1) 0.07 ± 0.04
BUN (mg·dL−1)
Creatinine (mg·dL−1)
-GT (U·L−1)

Female
Sodium (mEq·L−1)
Potassium (mEq·L−1)
Glucose (mg·dL−1)
Triglyceride (mg·dL−1)
Cholesterol (mg·dL−1)
Uric acid (mg·dL−1)
ALP (U·L−1)
AST (U·L−1)
ALT (U·L−1)
Total protein (g/dL)
Total bilirubin (mg·dL−1) 0.15 ± 0.08
(mg·dL−1)
Creatinine (mg·dL−1)
-GT (U·L−1)

The data are expressed as mean ± SEM. * , compared with control group (ANOVA or Kruskal-Wallis test).