Research Article
Acute and Chronic Toxicity of an Aqueous Fraction of the Stem Bark of Stryphnodendron adstringens (Barbatimão) in Rodents
Table 4
Biochemical parameters in male and female rats orally treated with F2 of S. adstringens for 90 days.
| Parameters | Controls | F2 (mg·kg−1) | 10 | 100 | 200 |
| Male | Sodium (mEq·L−1) | | | | | Potassium (mEq·L−1) | | | | | Glucose (mg·dL−1) | | | | | Triglyceride (mg·dL−1) | | | | | Cholesterol (mg·dL−1) | | | | | Uric acid (mg·dL−1) | | | | | ALP (U·L−1) | | | | | AST (U·L−1) | | | | | ALT (U·L−1) | | | | | Total protein (g/dL) | | | | | Total bilirubin (mg·dL−1) | |
0.07 ± 0.04 | | | BUN (mg·dL−1) | | | | | Creatinine (mg·dL−1) | | | | | -GT (U·L−1) | | | | |
| Female | Sodium (mEq·L−1) | | | | | Potassium (mEq·L−1) | | | | | Glucose (mg·dL−1) | | | | | Triglyceride (mg·dL−1) | | | | | Cholesterol (mg·dL−1) | | | | | Uric acid (mg·dL−1) | | | | | ALP (U·L−1) | | | | | AST (U·L−1) | | | | | ALT (U·L−1) | | | | | Total protein (g/dL) | | | | | Total bilirubin (mg·dL−1) | |
0.15 ± 0.08 | | | (mg·dL−1) | | | | | Creatinine (mg·dL−1) | | | | | -GT (U·L−1) | | | | |
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The data are expressed as mean ± SEM. *, compared with control group (ANOVA or Kruskal-Wallis test).
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