Protective Effect of Standardized Extract of Ginkgo biloba against Cisplatin-Induced Nephrotoxicity

Table 2

The effect of EGb on changes of tissue BUN, creatinine, and MDA as well as NO levels in control and study groups.

	Dose; (mg/kg)	BUN; (mg/dL)	Creatinine; (mg/dL)	MDA; (nmol/g wet tissue)	NO; (μmol/g wet tissue)
Control		11.12±3.22	0.56±0.12	6.55±1.22	0.63±0.12
CDDP	10	84.21±13.45^∗	1.72±0.28^∗	12.31±3.27^∗	1.26±0.39^∗
EGb	200	10.31±2.63	0.58±0.17	5.84±1.18	0.72±0.19
CDDP + EGb		43.26±9.53^#	1.15±0.23^#	8.03±2.34^#	0.89±0.15^#

Each value is expressed as mean ± S.D. (𝑛=10/group); ^∗𝑃<0.05 versus saline; ^#𝑃<0.05 versus CDDP.