Research Article

Antihyperglycemic Effects of Short Term Resveratrol Supplementation in Type 2 Diabetic Patients

Table 2

Anthropometric, clinical, and biochemical parameters for placebo and resveratrol groups before and after resveratrol supplementation.

Control/placebo groupIntervention/resveratrol group
BaselineAfter 45 daysP valueBaseline treatmentAfter treatmentP value

Body weight (kg) 0.809 0.712
BMI (kg/m2) 0.332 0.395
Systolic blood pressure (mmHg) 0.147 <0.0001*
Diastolic blood pressure (mmHg) 0.279 0.169
Fasting glucose (mg/dL) 0.002* <0.0001*
Insulin (µIU/mL) 0.642 <0.0001*
HbA1c 0.764 <0.0001*
HOMA-IR 0.423 <0.0001*
HOMA-β 0.039 0.009*
Triglyceride (mg/dL) 0.145 0.051
Total cholesterol (mg/dL) 0.424 0.156
HDL-cholesterol (mg/dL) 0.133 0.001*
LDL-cholesterol (mg/dL) 0.003* 0.106
SGOT (IU/L) 0.212 0.837
SGPT (IU/L) 0.202 0.365
GGT (IU/L) 0.545 0.441
ALP (IU/L) 0.001* 0.372
Creatinine (mg/dL) 0.281 0.098

Data is presented as means ± SD. versus before treatment. HOMA-β: homeostasis model of assessment for beta cell function; HOMA-IR: homeostasis model of assessment for insulin resistance; HbA1c: Hemoglobin A1c; HDL: high density lipoprotein; LDL: low density lipoprotein; TG: triglyceride; SGOT: serum glutamate oxaloacetate transaminase; SGPT: serum glutamate pyruvate transaminase; GGT: gamma-glutamyltransferase; ALP: alkaline phosphatase.