Comparison of Brazilian Plants Used to Treat Gastritis on the Oxidative Burst of Helicobacter pylori-Stimulated Neutrophil

Table 1

Effects of methanolic extract of Brazilian plants used to treat gastritis on luminol-dependent chemiluminescence response of neutrophil stimulated by H. pylori.

Botanical name; (popular name)	Concentration; (µg/mL)	IA^a	% reduction in IA^b	EC50^c (µg/mL)
Alchornea glandulosa; (tapiá)	0 (control)	2.96×10^5±12542	—	43.4
	5	2.32×10^5±9838	21.6*
	50	0.54×10^5±2279	81.6*
	100	0.52×10^5±2197	82.4*
Alchornea triplinervia; (tanheiro)	0 (control)	2.34×10^5±11565	—	36.6
	5	1.67×10^5±8245	28.6*
	50	0.26×10^5±1301	88.9*
	100	0.23×10^5±1144	90.2*
Anacardium humile; (cajuzinho-do-cerrado)	0 (control)	2.20×10^5±13718	—	40.2
	5	2.00×10^5±8077	9.1
	50	0.21×10^5±2047	90.5*
	100	0.11×10^5±1113	95.0*
Byrsonima basiloba; (murici-de-ema)	0 (control)	2.90×10^5±3502	—	42.9
	5	2.92×10^5±8077	0
	50	0.30×10^5±2376	89.7*
	100	0.19×10^5±464	93.4*
Byrsonima intermedia; (murici-do-campo)	0 (control)	1.43×10^5±9123	—	56.8
	5	1.22×10^5±7767	14.6
	50	0.57×10^5±3648	60.1*
	100	0.37×10^5±2373	74.1*
Davilla elliptica; (cipó-de-carijó)	0 (control)	2.98×10^5±16869	—	41.1
	5	2.80×10^5±15811	6.0
	50	0.29×10^5±1651	90.3*
	100	0.16×10^5±891	94.6*
Qualea grandiflora; (pau-da-terra)	0 (control)	2.18×10^5±7691	—	39.3
	5	1.95×10^5±6878	10.5
	50	0.15×10^5±867	93.1*
	100	0.14×10^5±765	93.6*
Qualea parviflora; (ipê-cascudo)	0 (control)	2.20×10^5±18681	—	27.2
	5	1.14×10^5±9655	48.0*
	50	0.14×10^5±1194	93.6*
	100	0.11×10^5±931	95.0*
Qualea multiflora; (cerrado-campo)	0 (control)	2.60×10^5±22417	—	27.7
	5	1.37×10^5±11586	47.3*
	50	0.17×10^5±1432	93.5*
	100	0.13×10^5±1117	95.0*
Mouriri pusa; (puçá)	0 (control)	2.30×10^5±4038	—	42.4
	5	2.30×10^5±4127	0
	50	0.18×10^5±520	92.2*
	100	0.16×10^5±459	93.0*
Quercetin (standard)	0 (control)	2.48×10^5±5987	—	<1.0
	1	1.11×10^5±3211	55.2*
	5	0.18×10^5±1101	92.7*
	50	0.15×10^5±578	94.0*
	100	0.13×10^5±499	94.8*

aIntegrated area of chemiluminescence curve: mean of triplicate readings ± SD (𝑛=3); ^bcompared to the control; ^cefficient concentration; *statistically significant difference (𝑃<0.05).