Use of Propolis Hydroalcoholic Extract to Treat Colitis Experimentally Induced in Rats by 2,4,6-Trinitrobenzenesulfonic Acid

Table 1

The characteristics of stools from rats that received rectal TNBS (to induce colitis) or saline solution (S) after 5 or 12 days of treatment with propolis hydroalcoholic solution (TNBS-P and SP) or mesalazine solution (TNBS-M). The animals were euthanized 7 or 14 days after the colitis was induced. The results are expressed as the mean ± standard deviation (𝑛=5).

Group/time (days)	Characteristics of stools (0–2); (0) Well-formed pellets; (1) Liquid stools stuck to the anus, no bleeding; (2) Liquid stools and blood stuck to the anus
	Day 7	Day 14
S	0^a	0^a
TNBS	2.0±0^b	1.6±0.55^b
SP	0^a	0^a
TNBS-P	1.6±0.55^b	1.0±0^ab
TNBS-M	1.0±0^ab	1.0±0^ab

^a,bMeans followed by different letters in the same column are significantly different according to the Kruskal-Wallis test and Dunn’s post-test (𝑃<0.05).