Therapeutic Effect of the Tuber of Alisma orientale on Lipopolysaccharide-Induced Acute Lung Injury
Figure 2
EEAO posttreatment suppresses bioluminescence in an LPS-induced ALI mouse model. Prior to i.t. spraying of EEAO (300 mg/kg body weight), NF-κB reporter mice ( per group) received an i.p. injection of LPS (10 mg/kg body weight). At 2 h after LPS treatment, the reporter mice received an i.t. EEAO spraying to the lung. Baseline photon counts were obtained right after LPS challenge so that each mouse could be used as its own control (0 h). Bioluminescence was measured at the indicated time points after LPS injection following an i.p. luciferin injection. Shown are representative bioluminescence images of the chest of the reporter mice.
