Brazilein from Caesalpinia sappan L. Antioxidant Inhibits Adipocyte Differentiation and Induces Apoptosis through Caspase-3 Activity and Anthelmintic Activities against Hymenolepis nana and Anisakis simplex
Antioxidant activity of brazilein. (a) Chemical structure of brazilein from C. sappatin L. M.W. = 284. (b) DPPH• and (c) ABTS•+ free radical scavenging activities of brazilein and trolox (5, 10, 20, 30, 40, 50, and 100 μM). (d) Inhibition of lipid peroxidation by brazilein, trolox, and rutin (5, 10, 20, 30, 40, 50, and 100 μM) using liposome as an oxidizable substrate. Data are presented as from three independent experiments; indicates significant difference from vehicle-treated cells.