Brazilein from Caesalpinia sappan L. Antioxidant Inhibits Adipocyte Differentiation and Induces Apoptosis through Caspase-3 Activity and Anthelmintic Activities against Hymenolepis nana and Anisakis simplex
Effect of brazilein on H. nana. Treatment with various concentrations of brazilein (10, 50 and 100 μM) with incubation times of 2, 4, 6, 12, 24, 48, and 72 h on H. nana, respectively. Time course of effect on oscillation (A) and peristalsis (B) of H. nana of brazilein presented as percentages. Vehicle is 0.1% DMSO solvent. Each value is presented as of three individual experiments; indicates a significant difference from the result for vehicle-treated worms.