Therapeutic Effect of C-Phycocyanin Extracted from Blue Green Algae in a Rat Model of Acute Lung Injury Induced by Lipopolysaccharide
Effects of CPC on LPS-induced NF-κB activation, iNOS and COX-2 expressions in lungs. The expression of nuclear phosphorylation-p65NF-κB (a), iNOS and COX-2 (b) in lungs was determined by Western blot 6 h after LPS challenge. For NF-κB nuclear translocation assay, the nuclei of these cells visualized by Hoechst 33285 staining (blue) and the p65NF-κB expression (green) were detected in lungs. The merged figures indicated the translocation of p65NF-κB to nuclei. The figures are representative of four similar experiments. Data are presented as the mean ± SEM (). *, *** compared with control group; # compared with LPS group.